What is collie eye anomaly (CEA)? CEA is an eye condition that affects dogs. Collies are often diagnosed with the genetic form of CEA, hence the name. The condition can affect the entire eye or part of the eye, and it can be seen in one or both eyes. If you're concerned that your dog may have CEA, read on to learn more about the causes, clinical signs, treatment and more.
Collie Eye Anomaly Causes

True to its name, the genetic form of CEA is usually diagnosed in collies and collie crosses. Australian shepherds, Shetland sheepdogs and border collies are also affected. Some less common breeds that are affected by genetic CEA include the Boykin spaniel, the longhaired whippet, the silken windhound, the Hokkaido dog, the Lancashire heeler and the Nova Scotia duck tolling retriever. The problem in CEA is that an area of the retina (the nerve layer of the eye with rods and cones) and/or the choroid (the choroid is the blood vessel layer under the retina) does not develop the way it should because of DNA mutations. CEA is inherited in an autosomal recessive manner, meaning dogs will only develop this disorder if they have two copies of the gene mutation, one from each parent, that causes this defect.
- Spontaneous: The spontaneous form of CEA occurs when something affects the normal development of a puppy's eye while they're growing in the womb. The spontaneous form of CEA can occur if the mother experiences a systemic infection or inflammation, is exposed to a toxin or is malnourished during pregnancy. In both forms of CEA, the blood vessels that deliver blood to the retina are underdeveloped and too small, leading to abnormal development of the eye.
Clinical Signs of Collie Eye Anomaly
While blindness is often the first sign pet parents note, other signs of CEA in dogs include:
- A small eyeball
- A sunken appearance to the eyeball
- An eye that looks cloudy
Clinical signs of CEA are usually first seen in very young dogs. If you notice any of these signs or if you suspect that your puppy is going blind, call your veterinarian to get your dog seen as soon as possible.
