The best way to care for your furry friend is to understand how their body works and to know what to look for when it comes to their health and well-being. Lymphoma in cats is a malignant cancer of the lymphatic system, which is a collection of lymphocytes (blood cells) and organs (lymph nodes, etc.). It can affect many systems in a cat's body, leading to intestinal lymphoma in cats, and is the most common cause of spinal cord tumors.
Here's what you need to know about lymphoma so you can be the most informed pet parent you can be.
Lymphoma in Cats
According to PetCure Oncology, feline lymphoma accounts for 30% of all cancer diagnosed in cats. The most common location for lymphoma is in the intestinal tract. Also known as gastrointestinal (GI) or alimentary lymphoma, intestinal lymphoma in cats can cause vomiting and diarrhea.
There are many types of lymphoma in cats, however, and a variety of factors will determine how this cancer might affect your kitty.

Causes
The onset of feline lymphoma has been linked to the feline leukemia virus (FeLV), and, to a lesser extent, feline immunodeficiency virus (FIV). Cats who are positive for feline leukemia generally develop cancer at a younger age.
These days, because many cats are housed indoors and there's widespread testing for and vaccination against FeLV, lymphoma is less common in younger cats. Cats who are negative for the virus tend to develop lymphoma at an older age. The American Journal of Epidemiology suggests that chronic exposure to cigarette smoke may also be a risk factor for lymphoma.
Types
Because the lymphatic system interacts with every system in the body, lymphoma can affect any of these systems. The main types of lymphoma include:
- Alimentary (digestive tract, most common)
- Mediastinal (chest)
- Renal (kidneys)
- Nasal (nose)
- Spinal (spine)
- Cutaneous (skin)
- Multicentric (meaning multiple systems are affected, most often the spleen and liver)
Signs
Signs of lymphoma depend on which organs are affected. Here are some of the signs to look out for according to where the lymphoma is located:
- Chest: Open-mouth breathing, coughing, loss of appetite, weight loss and regurgitation
- Digestive tract: Vomiting, diarrhea, constipation, loss of appetite, weight loss, lethargy and bloody stool
- Kidneys: Excessive drinking and urinating, weight loss and loss of appetite
- Nose: Chronic nasal discharge, bloody nose, swollen nose, sneezing, loss of appetite, eye discharge and noisy breathing
- Spine: Weakness or paralysis of the back legs
- Skin: Itching, hair loss and bleeding skin tumors
If you notice any of these signs in your cat, immediately contact your veterinarian. They can diagnose your cat's condition and determine the best treatment.
