Your cat’s kidneys play a vital role in maintaining her health. They help control her blood pressure, regulate the bloodstream, produce important hormones, enzymes, and red blood cells, as well as remove metabolic waste from the blood. If the cat’s kidneys aren’t able to do their job properly, this can lead to significant, life-threatening problems for your cat.
Common Causes of Cat Renal Failure
Kidney failure is one of the most common causes of severe illnesses in cats, especially in older cats. There are two categories of renal failure in cats: acute renal failure and chronic renal failure. Signs of acute renal failure usually manifest over a week or month’s time, while chronic renal failure is present for a longer period. The risk for cat kidney disease is higher in certain breeds like Persians and Angoras, but the disease is typically acquired.
Potential causes of kidney failure in cats include:
- Decreased blood or urine flow to the kidneys
- High blood pressure
- Cancer
- Obstructions such as kidney stones
- Ingestion of toxic substances, such as antifreeze, pesticides, medications and cleaning chemicals
- Advanced dental disease
- Some long-haired breeds (such as Persians and Angoras) have a genetic predisposition to the disease
- Age older than seven years
- A food high in phosphorus or increased levels of protein can increase the disease’s progression
- Outdoor cats have a higher risk for acute problems due to their potential increased exposure to toxins
Signs of Kidney Failure in Cats
Common signs of kidney failure in cats may be difficult to detect because of their similarities to other disorders like diabetes and hyperthyroidism. Unfortunately, kidney failure is a progressive disease, and symptoms may not be apparent for a long time.
If you notice any of these signs in your cat, contact your vet:

- Reduced appetite
- Increased thirst
- Frequent or no urination
- Bloody or cloudy urine
- Vomiting
- Poor coat appearance
- Lethargy and depression
- Weight loss
- Bad breath
- Sore mouth or mouth ulcers
- Diarrhea or constipation
- Increased sleeping